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This document pertains to lyophilized powder supplied for laboratory applications

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Reducing glutathione production in lymphoma cells, either through pharmacological inhibition of glutamate cysteine ligase (GCL), the enzyme catalyzing the rate-limiting step in glutathione biosynthesis, or via knockdown of GCLC , the GCL catalytic subunit, sharply decreased cell growth in 3D gels and xenografts

CBS Firstly, homocysteine is converted to an intermediate metabolite called cystathionine using the CBS enzyme (cystathionine beta synthase)

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10.1371/journal.ppat.1003573 PLoS Pathog